Now in its thoroughly revised, updated Fifth Edition, this volume is a comprehensive, practical reference on contemporary methods of disinfection, sterilization, and preservation and their medical, surgical, and public health applications. More than a third of this edition's chapters cover subjects never addressed in previous editions. New topics covered include recently identified pathogens, microbial biofilms, use of antibiotics as antiseptics, synergism between chemical microbicides, pulsed-light sterilization of pharmaceuticals, and new methods for medical waste management. Close attention is given to infection control problems posed by endoscopes, implants, prostheses, and organ transplantation and to prevention of opportunistic infections in immunocompromised patients. A Brandon-Hill recommended title.