In recent years, cutting-edge genomic and molecular techniques have profoundly influenced the direction of brain tumor research and modern clinical practice. Genomic and Molecular Neuro-Oncology, edited by Wei Zhang and Gregory N. Fuller, is an up-to-date reference that documents these important advances and describes their medical and therapeutic implications. Written for a broad range of researchers and clinicians including oncologists, neurologists, pathologists, neuroscientists, residents, postdoctoral fellows, and others in related fields, this volume contains 18 contributions organized in five sections: Genomic and Genetic Alterations in Gliomas, Molecular Alterations in Gliomas, Genomics and Informatics, Animal Models, and Molecular Therapeutics. Each chapter provides a review of a specific subfield of contemporary molecular neuro-oncology, including recently implemented diagnostic and research applications. Table of Contents Part I: Genomic and Genetic Alterations in Gliomas Ch. 1: Methylation and Genomic Damage in Gliomas; Oliver Bogler and Webster K. Cavenee Ch. 2: Molecular and Clinical Aspects of 1p-19q Loss in Oligodenroglioma; J. Matthew McDonald, Howard Colman, Arie Perry, Ken Aldape Ch. 3: Functional Inactivation of p53 in Gliomas; Woonyoung Choi, Federick Lang, Wei Zhang Ch. 4: PTEN: A Tumor Suppressor Gene Frequently Mutated in Glioblastomas; Michael Davies Ch. 5: Molecular Genetics of the SWI/SNF Family Gene INI1 in Atypical Teratoid/Rhabdoid T